Trong tế bào người luôn tồn tại song song hai hệ ADN, ADN nhân và ADN ty thể. Vì có cấu trúc dạng vòng nên ADN ty thể tồn tại bền vững hơn và được bảo toàn tốt trong răng và xương.
Giám định hài cốt là phương pháp phân tích ADN trong đó một trong hai mẫu được phân tích là mẫu răng và xương được lấy từ hài cốt, mẫu còn lại từ người còn sống cho mẫu được giả định mối quan hệ theo dòng mẹ (phân tích ADN ty thể).
Loại xét nghiệm:
ADN ty thể di truyền theo dòng ngoại thườngbà ngoại, dì, mẹ, các cháu gái…(Phân tích vùng HV1 và HV2 của ADN ty thể)
Thu mẫu xét nghiệm:
Mẫu hài cốt: Lấy 3 – 5 răng hoặc xương còn chắc
Mẫu đối chứng: Thu các loại mẫu: máu, niêm mạc miệng, tóc, móng…
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